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Functional analysis is PCAT14.
A. Schematic representation of the workflow to endogenously overexpress PCAT14 in prostate cancer cells using CRISPR/SAM system. B. Bar plots represent fold increase in PCAT14 level in PC3 cells expressing dCas9–VP64 and MS2–p65–HSF1 with control or 2 independent PCAT14 sgRNAs. C. Bar plot represent quantification of invaded PC3 cells with or without PCAT14 expression. D. Representative images of invaded PC3 cells with or without PCAT14 expression.
