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. 2016 Sep 10;15:80. doi: 10.1186/s12937-016-0198-1

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Changes in the primary outcome parameter over the study period. The figure shows change from baseline in GSRS total mean score in the two treatment groups, throughout the intervention period. 178 subjects were included in the analysis, excluding participants taking PPI and GMMS during the study. (Prob) indicates the probiotic group receiving treatment with L. reuteri (n = 86) and (PL) indicates the placebo group (n = 92)