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. Author manuscript; available in PMC: 2017 Feb 17.
Published in final edited form as: Nature. 2016 Aug 18;536(7616):285–291. doi: 10.1038/nature19057

Extended Data Figure 4. Number of protein-truncating variants in constrained genes per individual by allele frequency bin.

Extended Data Figure 4

Equivalent to Figure 5b limited to constrained (pLI ≥ 0.9) genes.