Table 2.
Hospitalization or ER visit for acute toxicity
| Toxicity | CTRT | RT Only | |
|---|---|---|---|
| No. (%) | No. (%) | p-value | |
| Any toxicity | 934 (62) | 358 (46) | <0.0001 |
| By diagnostic category | |||
| Oral | 447 (30) | 142 (18) | <0.0001 |
| Dysphagia | 301 (20) | 121 (16) | 0.0100 |
| Mucositis | 182 (12) | 21 (3) | <0.0001 |
| Esophagitis | 73 (5) | 17 (2) | 0.0020 |
| Gastrointestinal | 149 (10) | 23 (3) | <0.0001 |
| Nausea, vomiting | 106 (7) | 17 (2) | <0.0001 |
| Diarrhea | 59 (4) | <11 | <0.0001 |
| Dehydration | 240 (16) | 41 (5) | <0.0001 |
| Hematologic | 469 (31) | 108 (14) | <0.0001 |
| Neutropenia | 162 (11) | <11 | <0.0001 |
| Thrombocytopenia | 63 (4) | <11 | 0.0002 |
| Anemia | 353 (24) | 98 (13) | <0.0001 |
| Infection | 372 (25) | 169 (22) | NS |
| Infection | 318 (21) | 135 (17) | 0.0336 |
| Aspiration pneumonia | 126 (8) | 66 (8) | NS |
| Fever | 93 (6) | 14 (2) | <0.0001 |
| Acute renal failure | 139 (9) | 37 (5) | 0.0001 |
| Cardiac | 247 (16) | 127 (16) | NS |
| PE/DVT | 64 (4) | 16 (2) | 0.0070 |
| Other | 116 (8) | 16 (2) | <0.0001 |
| Delirium/drug psychoses | 87 (6) | 16 (2) | <0.0001 |
| Non-specific | 35 (2) | 0 (0) | <0.0001 |
Notes: Table shows percent of patients in each group who had a hospitalization or ER visit within each diagnostic category. Cell counts <11 not shown in accordance with SEER-Medicare Data Use Agreement
Abbreviations: CTRT, chemoradiation; RT, radiation; PE/DVT, pulmonary embolism/deep vein thrombosis; NS: Not statistically significant at p<0.05