. Author manuscript; available in PMC: 2017 Dec 1.

Published in final edited form as: Clin Genitourin Cancer. 2016 Mar 10;14(6):511–517. doi: 10.1016/j.clgc.2016.03.006

Table 2.

Summary of Genotype Association Results in the Discovery Cohort

SNP	Recessive allele (frequency)^*	Association with pT0^†		Association with <pT2 (downstaging)^‡
SNP	Recessive allele (frequency)^*	OR	P value	OR	P value
rs10964552	A (0.13)	NA	NA	0.20	0.017
rs1649942	C (0.20)	0.00	0.994	1.02	0.963
rs2136241	C (0.46)	0.82	0.795	1.08	0.832
rs2191934	T (0.47)	0.42	0.300	1.26	0.535
rs244898	T (0.41)	6.82	0.006	1.60	0.192
rs3893319	G (0.05)	NA	NA	1.93	0.471
rs6870861	C (0.11)	0.00	0.992	0.38	0.131
rs7937567	G (0.38)	4.75	0.040	0.95	0.885
rs9527419	T (0.14)	NA	NA	1.09	0.871

allele frequency in the discovery cohort of this study

OR= odds ratio

^†

using recessive genetic model. OR are calculated using the major allele as the reference (comparator). NA: for these results, OR and P values are not provided since these were test instances where there were either zero or only one homozygous recessive patient present in the cohort. OR and P values for these situations in a recessive model were therefore undependable.

^‡

using additive genetic model; the OR is expressed for the impact of carriage of increasing copies of the minor allele