Figure S6.

Broad Neutralization of Near-Native Viruses by VRC01-gH mAbs, Related to Figure 5

Neutralization of a 25-virus panel consisting of near-native (N276A) viruses, with IC50 values shown in μg/ml. Antibodies are grouped by the mouse from which they were isolated. Blank entries indicate lack of neutralization (> 10 μg/ml), and antibody/virus combinations that were not tested are noted (ND). Neutralization by mature VRC01 is shown for comparison. Tier phenotypes for the parent viruses lacking the N276A mutation were taken from (Binley et al., 2004, Seaman et al., 2010, Sellhorn et al., 2012, Hraber et al., 2014).