Table 1. Binding Energies of the Wild and Mutant HBsAg in Complex with MAb12.

	MAb12
HBsAg type	Center Energy	Lowest Energy	Cluster No.a	“a” Determinant H-Bond No.
Wild-type HBsAg	-601.8	-626.7	177	14
G145R mutant HBsAg	-290.9	-309.1	66	10

^aThe cluster with the largest number of low-energy structures typically contains the native fold.