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. Author manuscript; available in PMC: 2016 Sep 11.
Published in final edited form as: J Immunol. 2012 Oct 5;189(9):4478–4487. doi: 10.4049/jimmunol.1200885

Figure 3. IE8 bound to BF2*0401 and the positively charged pockets in the BF2*0401 groove.

Figure 3

(A) Interactions between IE8 and BF2*0401. Side chains of residues involved are labelled and coloured in pink for the BF2*0401 and green for the IE8. Salt bridges and hydrogen bonds are illustrated as dashed lines in teal. (B) The BF2*0401 peptide-binding groove demonstrates an entirely positive charged surface. The electrostatic surface potential was generated with PyMOL. Red is electronegative and blue is electropositive. Yellow arrows represent the pockets holding the anchor residues. (C) The P2 Asp is shown as a stick in green. Residues forming the B pocket in BF2*0401 are shown in pink on the surface. (D) The P5 Asp and residues forming the C pocket in BF2*0401 are shown. (E) The P8 Glu and residues forming the F pocket in BF2*0401 are shown.