Skip to main content
. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Hear Res. 2016 May 31;339:32–39. doi: 10.1016/j.heares.2016.05.015

Figure 1.

Figure 1

(A) shows placement of the hypothermia probe in contact with an excised rat left cochlea. The inserted electrode analog and a thermistor placed at the round window for temperature measurement are highlighted. Fluorocarbon cooled by an external peltier element is circulated through the copper tip of the probe. RW-round window, SA-stapedial artery, OW-oval window, S-stapes. (B) With the custom-designed thermoelectric cooler and probe positioned anteroinferior to the RW, the cochleae were cooled between 4–6°C within 10 minutes. The temperature was maintained for 20 minutes prior to insertion of the electrode analog. Hypothermia was maintained for further 20 minutes prior to a gradual rewarming of the cochleae over 10 minutes. Inset shows the level of cooling achieved at the round window measured prior to electrode insertion in animals undergoing chronic insertion.