Skip to main content
. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Curr Opin Chem Biol. 2016 Jun 25;33:135–141. doi: 10.1016/j.cbpa.2016.06.004

Figure 2. Selectivity profile of UNC3866.

Figure 2

UNC3866 antagonizes the Kme reading function of the Polycomb CBX and the CDY families of chromodomains and is highly selective over >250 other protein targets evaluated. The affinity of UNC3866 for its chromodomain targets was determined by ITC.