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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Brain Res. 2016 Jul 26;1648(Pt A):181–192. doi: 10.1016/j.brainres.2016.07.035

Figure 2. LPS blunted fasting induced c-fos activation in NPY-GFP mice.

Figure 2

(a) Fasting increased c-fos expression in NPY neurons (Fasted/S vs Fed/S); while LPS blocked fasting-induced c-fos expression in NPY/AgRP neurons at the 24 hour time point (Fasted/L). LPS had no effect on c-fos expression in fed mice (Fed/L). White arrows indicate cells in which NPY/AgRP and c-fos are colocalized. (b) Bar graphs represent the percentage of c-fos and GFP colocalized cells. Different letters indicate statistical significance among the four groups determined by two-way ANOVA followed by Tukey’s multiple comparison test (p<0.05; n=3 mice/group).Scale bar: 100 μM. 3V: 3rd cerebral ventricle. Bars with the same letter are not statistically different (p>0.05). ME: Median Eminence. The data are presented as mean ± standard error of the mean (SEM).