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Interaction of central GLP-1 and GnRH neuronal systems. (A) Red GLP-1-immunoreactive (IR) axons (arrowheads) and a green GnRH-IR neuron (arrows) appear in the vicinity of the vascular organ of lamina terminalis (OVLT) of the mouse brain. (B,C) GLP-1-IR axons establish contacts with the dendrites (enframed by dotted line) of a subset of GnRH neurons exhibiting smooth (B) or rough (C) surface. The multiple contacts (arrowheads) are shown at higher power in insets (B1,C1).
