Table 3.
Biological effective dose (BED) values for heart, lung, most exposed rib segment, and skin
| HDR-BT [Gy] | EBRT [Gy] | p-value | |
|---|---|---|---|
| Heart Dmax | 5.37 (4.00-7.76) | 10.73 (8.49-16.36) | < 0.01 |
| Heart Dmax left-sided irradiation (α/β = 3) | 8.83 (5.90-13.30) | 14.47 (10.4-21.37) | < 0.01 |
| Heart Dmax right-sided irradiation (α/β = 3) | 4.29 (3.85-5.20) | 9.27 (7.64-10.94) | < 0.01 |
| Lung Dmax (α/β = 3) | 12.61 (8.70-17.00) | 32.47 (27.64-34.46) | < 0.01 |
| Lung Dmean (α/β = 3) | 4.24 (3.80-5.10) | 5.92 (5.05-6.63) | < 0.01 |
| Rib Dmax (α/β = 3) | 15.92 (10.80-21.52) | 36.12 (35.18-36.83) | < 0.01 |
| Skin Dmax (α/β = 2.8) | 16.20 (11.37-27.17) | 37.27 (33.36-39.01) | < 0.01 |
HDR-BT – high-dose-rate interstitial brachytherapy, EBRT – external beam radiotherapy, Dmax – maximum dose [Gy], Dmean – mean dose [Gy]
Range: 25th quartile – 75th quartile