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. 2016 Aug;28(4):435–443. doi: 10.21147/j.issn.1000-9604.2016.04.07

5.

Genotype and allele frequencies of VEGI gene polymorphisms and Her-2 status

SNP ID Genotype Her-2 (+) No. (%) Her-2 (–) No. (%) OR (95% CI) P value
P^>0.05, P^^>0.05 after multiple testing by Haploview program using 10,000 permutations. VEGI, vascular endothelial growth inhibitor. Her-2, human epidermal growth factor receptor 2.
rs6478106 CC 54 (40.00) 215 (45.84) Reference
CT 62 (45.93) 224 (47.76) 1.102 (0.731-1.661) 0.642
TT 19 (14.07) 30 (6.40) 2.522 (1.320-4.818) 0.004
Dominant 1.270 (0.860-1.874) 0.229
Recessive 2.397 (1.302-4.411) 0.004
Allelic 1.355 (1.020-1.799) 0.036^
rs4979462 CC 68 (50.00) 257 (54.68) Reference
CT 50 (36.76) 189 (40.21) 1.000 (0.663-1.507) 0.999
TT 18 (13.24) 24 (5.11) 2.835 (1.455-5.523) 0.002
Dominant 1.207 (0.823-1.768) 0.335
Recessive 2.835 (1.489-5.397) 0.001
Allelic 1.371 (1.021-1.842) 0.035^^