S3.

Genotype and allele frequencies of VEGI gene polymorphisms and PR status

SNP ID	Genotype	PR (+) No. (%)	PR (-) No. (%)	OR (95% CI)	P value
VEGI, vascular endothelial growth inhibitor; PR, progestrogen receptor.
rs6478106	CC	176 (44.22)	93 (45.37)	Reference
	CT	187 (46.98)	99 (48.29)	0.998 (0.703-1.416)	0.992
	TT	35 (8.79)	13 (6.34)	1.423 (0.718-2.820)	0.311
	Dominant			1.047 (0.746-1.470)	0.789
	Recessive			1.424 (0.736-2.756)	0.292
	Allelic			1.087 (0.840-1.406)	0.525
rs4263839	GG	116 (28.86)	53 (24.88)	Reference
	GA	214 (53.23)	122 (57.28)	0.801 (0.541-1.188)	0.270
	AA	72 (17.91)	38 (17.84)	0.866 (0.520-1.442)	0.579
	Dominant			0.817 (0.560-1.192)	0.294
	Recessive			1.005 (0.651-1.550)	0.983
	Allelic			0.924 (0.730-1.170)	0.513
rs4979462	CC	214 (53.77)	111 (53.62)	Reference
	CT	157 (39.45)	82 (39.61)	0.993 (0.698-1.412)	0.969
	TT	27 (6.78)	14 (6.76)	1.000 (0.504-1.984)	0.999
	Dominant			0.994 (0.710-1.392)	0.973
	Recessive			1.003 (0.514-1.958)	0.992
	Allelic			0.997 (0.762-1.304)	0.981
rs7848647	TT	94 (23.62)	51 (24.64)	Reference
	TC	218 (54.77)	113 (54.59)	1.047 (0.695-1.577)	0.827
	CC	86 (21.61)	43 (20.77)	1.085 (0.658-1.789)	0.749
	Dominant			1.057 (0.715-1.564)	0.780
	Recessive			1.051 (0.696-1.587)	0.812
	Allelic			1.038 (0.818-1.316)	0.759