S5.
Genotype and allele frequencies of VEGI gene polymorphisms and TNBC status
| SNP ID | Genotype | TNBC No. (%) | Non-TNBC No. (%) | OR (95% CI) | P value |
| VEGI, vascular endothelial growth inhibitor; TNBC, triple negative breast cancer. | |||||
| rs6478106 | CC | 42 (43.30) | 227 (44.86) | Reference | |
| CT | 51 (52.58) | 235 (46.44) | 1.173 (0.750-1.835) | 0.484 | |
| TT | 4 (4.12) | 44 (8.70) | 0.491 (0.168-1.440) | 0.265 | |
| Dominant | 1.065 (0.687-1.651) | 0.777 | |||
| Recessive | 0.452 (0.158-1.287) | 0.153 | |||
| Allelic | 0.932 (0.668-1.301) | 0.680 | |||
| rs4263839 | GG | 22 (21.57) | 147 (28.65) | Reference | |
| GA | 60 (58.82) | 276 (53.80) | 1.453 (0.857-2.463) | 0.164 | |
| AA | 20 (19.61) | 90 (17.54) | 1.485 (0.768-2.873) | 0.238 | |
| Dominant | 1.461 (0.878-2.430) | 0.143 | |||
| Recessive | 1.146 (0.669-1.965) | 0.619 | |||
| Allelic | 1.202 (0.890-1.624) | 0.230 | |||
| rs4979462 | CC | 49 (50.52) | 276 (54.33) | Reference | |
| CT | 43 (44.33) | 196 (38.58) | 1.236 (0.789-1.935) | 0.355 | |
| TT | 5 (5.15) | 36 (7.09) | 0.782 (0.293-2.092) | 0.624 | |
| Dominant | 1.165 (0.755-1.800) | 0.490 | |||
| Recessive | 0.713 (0.272-1.864) | 0.488 | |||
| Allelic | 1.049 (0.743-1.482) | 0.785 | |||
| rs7848647 | TT | 28 (28.28) | 117 (23.12) | Reference | |
| TC | 52 (52.53) | 279 (55.14) | 0.779 (0.469-1.299) | 0.334 | |
| CC | 19 (19.19) | 110 (21.74) | 0.722 (0.381-1.366) | 0.315 | |
| Dominant | 0.763 (0.470-1.237) | 0.271 | |||
| Recessive | 0.855 (0.497-1.472) | 0.571 | |||
| Allelic | 0.857 (0.631-1.163) | 0.321 | |||