Fig. 2. MicroRNA (miRNA) molecular networks involved in chondrocyte differentiation and homeostasis. Each miRNA has specific target messenger RNAs and affect anabolic or catabolic signals in chondrocytes. MMP, matrix metalloproteinase; PDGFRα, platelet-derived growth factor receptors-alpha; IGFBP, insulin-like growth factor binding protein; Dnpep, aspartyl aminopeptidase; BMP, bone morphogenetic protein; TGF-β, transforming growth factor-beta.
