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. 2016 Sep 7;4:e2347. doi: 10.7717/peerj.2347

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©2016 Samuel et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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(A) ALP activity was significantly higher in the PRC treated cells compared to other groups at day 8 and 16; (B) Osteocalcin level gradually increased, peaking at day 24, with PRC group having the highest concentration throughout the study duration. The ALP activity and osteocalcin levels in each sample were normalized to the amount of DNA in the sample. Data are represented as the means ± SD. * denotes statistical significance between the indicated pairs (p < 0.05). (OM denotes osteogenic medium group).