Figure 1. Histopathological changes in lung tissue samples of the four groups. Hematoxylin and eosin stain (×100 magnification, bar 100 μm). A and B, NC and N-A groups (n=8): normal lung structure. C, uCIH group (n=8): increased alveolar wall thickness, edema, bleeding, and infiltration of inflammatory cells. D, CIH-A group (n=8): mild structural destruction and inflammatory infiltration. NC: normoxia control group; N-A: NC and Ang-(1–7) supplemented group; uCIH: untreated chronic intermittent hypoxia group; CIH-A: CIH and Ang-(1–7) supplemented group.
