Table S1.
Expression levels of surface markers on cNK and IL4-NK cells
Markers | cNK cells | IL4-NK cells |
Common NK marker | ||
CD49b** | 180.0 ± 6.1 | 86.1 ± 2.5 |
Maturation markers | ||
B220* | 20.2 ± 2.0 | 145.3 ± 17.4 |
CD11b*** | 189.7 ± 1.9 | 27.5 ± 2.4 |
TRAIL | 6.0 ± 0.7 | 5.1 ± 0.6 |
Activating receptors | ||
NK1.1* | 491.2 ± 21.4 | 720.0 ± 53.1 |
NKp46* | 325.7 ± 21.5 | 222.3 ± 26.0 |
NKG2D | 35.6 ± 0.8 | 27.2 ± 4.6 |
2B4* | 209.0 ± 16.4 | 681.3 ± 59.1 |
Ly108** | 9.3 ± 0.8 | 24.7 ± 2.4 |
Inhibitory receptors | ||
KLRG1 | 161.0 ± 33.0 | 73.2 ± 16.8 |
NKG2A*** | 30.6 ± 0.8 | 11.1 ± 0.3 |
Activation marker | ||
Thy1.1** | 294.3 ± 89.1 | 963.5 ± 133.9 |
Resting marker | ||
Ly6C** | 106.5 ± 11.2 | 28.6 ± 5.4 |
Cytokine receptors | ||
IL-4Rα* | 10.1 ± 0.9 | 31.0 ± 4.9 |
IL-7Rα | 5.3 ± 1.1 | 4.6 ± 0.1 |
IL-18Rα* | 26.6 ± 4.0 | 5.0 ± 0.3 |
IL-21Rα** | 4.5 ± 0.3 | 17.4 ± 0.9 |
The cNK cells in the liver were derived from the mice at 5 d after the injection with control vector (5 μg). The IL4-NK cells in the liver were derived from the mice at 5 d after the injection with pLIVE-IL-4 vector (5 μg). The numbers indicated MFI ± SEM of at least three separate experiments. *P < 0.05; **P < 0.01; ***P < 0.001.