Relation between LTD and changes of Rm. Ordinates, EPSC-amplitude during 25−29 min after induction of LTD by Cj. Abscissae, Rm-after/Rm-before LTD induction. (A) With (2PF + CF) Cj (protocol-2). (B) Similar to A, but with (2PF + depolariziation) Cj (protocol-3). Left plots, for WT mice. Center plots, for K882A mice. Right plots, for Δ7 mice. In A, correlation coefficient for WT, K882A or Δ7 was −0.46 (P = 0.36), −0.77 (P = 0.07), or 0.04 (P = 0.93), respectively. In B, correlation coefficient for WT, K882A, or Δ7 was 0.84 (P = 0.08), −0.15 (P = 0.75), or 0.15 (P = 0.78), respectively. No significant correlation was found between Rm-after/Rm-before ratio and LTD in any group. Horizontal and vertical bars indicate mean and SEM, respectively.