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. 2016 Sep 12;6:33162. doi: 10.1038/srep33162

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Heat-map showing hierarchical clustering according to normalized expression levels of genes that relate to angiogenesis, MMPs, and chemokines. Data are from nine independent experiments and were normalized to determine the log ratio with respect to the median expression of each gene. (b) GM-CSF, OSM, VEGF and CXCL8 concentrations were measured by ELISA at various times post-infection (n = 3 experiments) in supernatants from uninfected (diamond) and M. tuberculosis-infected ΜΦ (square) cultures.