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Subclassification of colorectal cancer cases associated with “hereditary nonpolyposis colorectal cancer” and microsatellite instability. AC, Amsterdam criteria; HNPCC, hereditary nonpolyposis colorectal cancer; MMR, mismatch repair; CMMR-D, constitutional MMR deficiency; CRC, colorectal cancer; MAP, MUTYH associated polyposis. *May present with LS type cancers in early adulthood, **WHO term “probably Lynch syndrome.”
