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. 2016 Sep 12;6:32497. doi: 10.1038/srep32497

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Copyright © 2016, The Author(s)

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Comparison of approximate calculation of the TPDF for drift and selection (Ns = 10, μ₁ = μ₂ = 0, solid lines – Eqn. 11) and numerical integration of stochastic differential equation that arises from diffusion approximation (solid circles). (a) initial frequency x₀ = 0.1, (b) x₀ = 0.5, (c) x₀ = 0.9. Green’s functions are plotted at times given by fractions of , which is approximately the expected time to fixation of a variant which survives drift and then is driven to fixation by selection³⁶.

Inline graphic — Comparison of approximate calculation of the TPDF for drift and selection (Ns = 10, μ₁ = μ₂ = 0, solid lines – Eqn. 11) and numerical integration of stochastic differential equation that arises from diffusion approximation (solid circles). (a) initial frequency x₀ = 0.1, (b) x₀ = 0.5, (c) x₀ = 0.9. Green’s functions are plotted at times given by fractions of , which is approximately the expected time to fixation of a variant which survives drift and then is driven to fixation by selection³⁶.