Table 3.
Associations of measures of sleep-disordered breathing with continuous ECG parameters
| Measure of SDBa | N | Mean (95 % confidence interval)
|
|||
|---|---|---|---|---|---|
| Resting HR | PR interval | QRS duration | QTc interval | ||
| %TST < 90 | |||||
| <1.0 (referent) | 238 | 61.7 (60.3–63.0) | 186.6 (182.0–192.0) | 102.2 (99.7–104.8) | 422.3 (419.0–425.7) |
| 1.0 to <3.5 | 116 | 62.4 (60.5–64.3) | 184.9 (177.7–192.1) | 101.9 (98.3–105.5) | 419.0 (414.3–423.9) |
| ≥3.5 | 117 | 64.9 (62.9–67.0) | 187.7 (180.0–195.4) | 99.2 (95.4–103.1) | 427.6 (422.5–432.7) |
| P for linear trend | 0.01 | 0.99 | 0.24 | 0.25 | |
| AHI | |||||
| <5.0 (referent) | 189 | 61.5 (60.0–63.0) | 188.6 (183.0–194.3) | 102.2 (99.4–105.1) | 423.3 (419.6–427.1) |
| 5.0 to <15.0 | 162 | 62.7 (61.1–64.3) | 187.1 (181.1–193.1) | 101.6 (98.6–104.7) | 421.8 (417.7–425.8) |
| ≥15.0 | 120 | 64.4 (62.4–66.3) | 182.5 (175.0–190.0) | 100.0 (96.3–103.6) | 423.1 (418.2–428.0) |
| P for linear trend | 0.03 | 0.22 | 0.37 | 0.87 | |
Twenty-two men with permanent pacemaker excluded from all analyses except those examining association between SDB and presence of permanent pacemaker; 23 men with atrial fibrillation were also excluded from analyses examining association between SDB and first-degree AV block
%TST < 90 percent of total sleep time with oxygen saturation <90 %, AHI apnea hypopnea index, HR heart rate, SDB sleep-disordered breathing
a
Models adjusted for age, site, β-blocker use, coronary heart disease, calcium channel blocker use, and use of antiarrhythmic medications