Table 2.
Subjects’ functional measurements of tidal volumes.
| Subject | Tidal Volume (mL) | ||
|---|---|---|---|
| Spirometry-baseda: Mean ± SD | MRI-measured (50% bins): | MRI-measured (25% bins): | |
| Adult 1 | 460 ± 20 530 ± 60 |
230 | 400 |
| Adult 2 | 890 ± 40 750 ± 90 |
230 | 380 |
| Adult 3 | 1070 ± 120 950 ± 180 |
780 | 1170 |
| Adult 4 | 600 ± 110 470 ± 50 |
240 | 370 |
| Adult 5 | 390 ± 90 360 ± 40 |
230 | 340 |
| Adult 6 | 440 ± 80 460 ± 60 |
200 | 340 |
| Physiologically-predictedb: | MRI-measured (50% bins): | MRI-measured (25% bins): | |
| Control 1 | 10.8–16.2 | 6.3 | 12.5 |
| Control 2 | 12.8–19.2 | 4.4 | 8.3 |
| Control 3 | 10.0–15.0 | 1.4 | 5.1 |
| Control 4 | 10.6–15.8 | 6.1 | 8.6 |
| Control 5 | 10.0–15.0 | 5.1 | 5.4 |
| Control 6 | 8.8–13.2 | 3.9 | 5.5 |
| BPD 1 | 12.0–18.0 | 3.9 | 5.1 |
| BPD 2 | 9.2–13.8 | 2.6 | 9.5 |
| BPD 3 | 14.8–22.2 | 5.5 | 9.8 |
| BPD 4 | 14.0–21.0 | 2.3 | 8.9 |
| BPD 5 | 12.4–18.7 | 5.2 | 14.7 |
| CDH 1 | 12.8–19.2 | 6.3 | 14.6 |
| CDH 2 | 12.0–18.0 | 3.1 | 7.9 |
| CDH 3 | 14.8–22.2 | 6.8 | 8.7 |
| CDH 4 | 11.6–17.4 | 3.3 | 4.4 |
| CDH 5 | 14.6–22.0 | 7.3 | 9.3 |
a
Two spirometry tests were performed, with three measurements per test.
b
Physiologically-predicted neonatal tidal volumes are calculated with the scaling factor 4–6 mL/kg (41).