Table 5.
Diagnostic Accuracy of CSF Erythrocytes and Xanthochromia for SAH
| Risk Factor | Sensitivity, % (95% CI) |
Specificity, % (95% CI) |
Positive LR (95% CI) |
Negative LR (95% CI) |
|---|---|---|---|---|
|
| ||||
| CSF RBC >1000 | ||||
| Czuczman 2013 | 65 (44-83) | 79 (72-84) | 3.09 (2.09-4.57) | 0.44 (0.26-0.75) |
| Perry 2015 | 93 (68-100) | 91 (88-93) | 10.25 (7.73-13.59) | 0.07 (0.01-0.49) |
| Pooled Accuracy | 76 (60-88) | 88 (86-90) | 5.66 (1.38-23.27) | 0.21 (0.03-1.66) |
|
| ||||
|
Xanthochromia – UK
NEQAS |
100 (16-100) | 83 (77-88) | 4.87 (2.71-8.73) | 0.20 (0.02-2.53) |
| Perry 2006 | 100 (48-100) | 98 (97-99) | 47.67 (26.67-85.20) | 0.08 (0.01-1.21) |
| Gangloff 2015 | 100 (59-100) | 95 (93-96) | 15.23 (1.58-146.73) | 0.13 (0.02-0.83) |
| Pooled Accuracy | ||||
|
| ||||
| Xanthochromia -- Visual | ||||
| Perry 2006 | 50 (1-99) | 97 (93-99) | 15.57 (3.25-74.54) | 0.52 (0.13-2.07) |
| Dupont 2008 | 93 (66-100) | 95 (89-98) | 19.13 (8.04-45.45) | 0.08 (0.01-0.50) |
| Gangloff 2015 | 80 (28-99) | 99 (98-99) | 62.31 (28.47-136.37) | 0.20 (0.04-1.17) |
| Pooled Accuracy | 31 (21-41) | 98 (97-99) | 28.79 (9.77-84.80) | 0.22 (0.06-0.80) |
|
| ||||
|
Xanthochromia --
Traditional |
||||
| Perry 2006 | 100 (16-100) | 29 (23-35) | 1.17 (0.70-1.96) | 0.57 (0.05-7.28) |
|
| ||||
|
Xanthochromia –
Chalmers/Kiley |
||||
| Perry 2006 | 0 (0-84) | 89 (84-93) | 1.49 (0.12-19.23) | 0.94 (0.56-1.56) |
|
| ||||
|
Xanthochromia –
Chalmers revised |
100 (16-100) | 29 (23-35) | 1.17 (0.70-1.96) | 0.57 (0.05-7.28) |
| Perry 2006 | ||||