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. 2016 Jun;13(6):842–849. doi: 10.1513/AnnalsATS.201512-824OC

Table 2.

Therapy

  Background Therapy (n = 84) Subsequent Therapy (n = 129)
Treatment naive (n = 45)   Of 45 patients:
    24 (53) PDE5I
    8 (18) ERA
    5 (11) CCB
    2 (4) PROST
    4 (9) PDE5I and ERA
    1 (2) PROST and ERA
    1 (2) diuretics alone
Background therapy Of 84 patients: Of 84 patients:
  23 (27) PDE5I 8 (10) PDE5I
  19 (23) ERA 13 (15) ERA
  11 (13) PROST 12 (14) PROST
  16 (19) PDE5I and ERA 3 (3) PDE5I and ERA
  10 (12) PDE5I and PROST 1 (1) PDE5I and PROST
  1 (1) PROST and ERA 2 (2) PROST and ERA
  4 (5) PDE5I, ERA, PROST 0 PDE5I, ERA, PROST
    21 (25) PAH therapy dose change
    6 (8) Behavioral modifications
    9 (11) Adjustment in non-PAH therapy
    9 (11) Enrollment in clinical trials or PR

Definition of abbreviations: CCB = calcium channel blocker; ERA = endothelin receptor antagonist; PAH = pulmonary arterial hypertension; PDE5I = phosphodiesterase type 5 inhibitor; PR = pulmonary rehabilitation; PROST = prostacyclin.

Data presented as n (%).