Figure 3.

Diagnostic flow diagram of Vanderbilt cohort according to hemodynamic profiles. After extraction of all first-time unique right heart catheterizations (RHCs), a number of exclusions were applied, including subjects with minimal data or extreme physiology, subjects with prior heart or lung transplant, and subjects with chronic thromboembolic pulmonary hypertension (PH) or complex congenital heart disease. Subjects were subsequently stratified by hemodynamic profile into absence of PH (noPH), precapillary PH (PCPH), and pulmonary venous hypertension (PVH). PCPH was further subdivided into pulmonary arterial hypertension (PAH) on the basis of elevated pulmonary vascular resistance (PVR) and absence of parenchymal lung disease. COPD: chronic obstructive pulmonary disease; ICD-9: International Classification of Diseases, Ninth Revision; ILD: interstitial lung disease; mPAP: mean pulmonary artery pressure; PWP: pulmonary wedge pressure;