. 2016 Sep;6(3):360–368. doi: 10.1086/688060

Table 2.

Hemodynamic changes in pulmonary normotensive versus hypertensive male wild-type and Cyp2c44 knockout (Cyp2c44^−/−) mice

	Wild type		Cyp2c44^−/−
	Control	Chronic hypoxic pulmonary hypertension	Control	Chronic hypoxic pulmonary hypertension
CI (mL/min/m²)	1,302 ± 89.38	308.1 ± 19.03^a	1,344 ± 114.8	304.6 ± 36.01^a
SV (μL)	29.83 ± 1.50	5.90 ± 0.91^a	28.50 ± 2.09	6.03 ± 0.50
EDV (μL)	84.78 ± 2.28	26.31 ± 2.56^a	72.96 ± 3.59	29.00 ± 2.59^a
ESV (μL)	60.20 ± 2.71	21.62 ± 1.87^a	48.64 ± 2.45	25.21 ± 2.39^a
LV stiffness (mmHg/μL)	4.31 ± 0.17	21.89 ± 4.91^a	4.43 ± 0.15	18.26 ± 3.85^a
Ea (mmHg/μL)	3.57 ± 0.13	14.63 ± 2.22^a	3.10 ± 0.22	14.49 ± 1.82^a
TPR (mmHg × min/mL)	7.58 ± 0.38	34.51 ± 4.38^a	6.92 ± 0.55	34.20 ± 2.90^a

^Note

Data are mean ± standard deviation. CI: cardiac index; Ea: arterial elastance; EDV: end-diastolic volume; ESV: end-systolic volume; LV: left ventricle; SV: stroke volume; TPR: total peripheral resistance.

P < 0.05 versus control; N = 5.