Table 1.
Effect of Ischemia-Reperfusion on Systolic and Diastolic Myocardial Function Measured by Ultrasonic Crystals and on End-Diastolic Stiffness Measured by SWI
| Stunned Group (I) (n = 5) | Baseline | After 15 min of Occlusion | After 30 min of Reperfusion | p Value |
|---|---|---|---|---|
| Heart rate, beats/min | 112.0 ± 13.0 | 106.0 ± 13.0 | 106.0 ± 11.0 | NS |
| EDP, mm Hg | 13.5 ± 3.0 | 14.5 ± 1.9 | 12.5 ± 2.3 | NS |
| ESP, mm Hg | 68 ± 11.3 | 62.1 ± 7.8 | 61.7 ± 11.8 | NS |
| %ΔL | 13.5 ± 3.0 | 1.9 ± 1.8† | 6.2 ± 4.7†‡ | <0.01 |
| Stiffness constant (crystals) | 9.7 ± 3.1 | Not evaluated | 10.2 ± 2.3 | NS |
| SWI ED stiffness, kPa | 1.8 ± 0.3 | 2.1 ± 0.6 | 2.3 ± 0.4 | NS |
| Infarcted Group (II) (n = 5) | Baseline | After 2 h of Occlusion | After 30 min of Reperfusion | p Value |
|---|---|---|---|---|
| Heart rate, beats/min | 118.0 ± 14.0 | 113.0 ± 37.0 | 110.0 ± 26.0 | NS |
| EDP, mm Hg | 13.1 ± 2.2 | 13.5 ± 5.9 | 14.7 ± 3.5 | NS |
| ESP, mm Hg | 72.0 ± 8.2 | 54.0 ± 14.2∗ | 55.9 ± 14.5∗ | <0.05 |
| %ΔL | 14.2 ± 1.2 | 1.3 ± 1.6† | 1.3 ± 1.7† | <0.01 |
| Stiffness constant (crystals) | 8.8 ± 2.3 | Not evaluated | 25.7 ± 9.5∗ | <0.05 |
| SWI ED stiffness, kPa | 1.7 ± 0.4 | 6.2 ± 2.2∗ | 12.1 ± 4.2†‡ | <0.01 |
Values are mean ± SD.
%ΔL = [(end-diastolic length – end-systolic length)/(end-diastolic length)].
EDP = end-diastolic pressure; ESP = end-systolic pressure; NS = nonsignificant; SWI = shear wave imaging.
∗
p < 0.05 with control.
†
p < 0.01 with control.
‡
p < 0.01 with ischemia.