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Cisplatin-induced EMT was dependent on DOCK1.
Notes: (A) Western blot analysis of DOCK1 expression in bladder cancer cells exposed to cisplatin. (B) After transfection with DOCK1 siRNA, the expression of DOCK1, E-cadherin, and vimentin was determined in the presence of cisplatin. ***P<0.001.
Abbreviations: EMT, epithelial–mesenchymal transition; DOCK1, dedicator of cytokinesis 1; siRNA, small interfering RNA.
