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Investigation of the in vitro drug release from the manufactured microspheres.
Notes: (A) In vitro dissolution profile from totarol-loaded microspheres in PBS incubated at 37°C over 90 days. (B) Released and unreleased amount of totarol in PLGA microspheres after incubation in PBS for 90 days. In both diagrams, the data points represent the mean of three replicates.
Abbreviations: PBS, phosphate-buffered saline; PLGA, poly(lactide-co-glycolide).
