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. 2016 Sep 6;10:2803–2813. doi: 10.2147/DDDT.S106216

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© 2016 McGowan et al. This work is published and licensed by Dove Medical Press Limited

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Brain distribution of ELP following IV and IN administration.

Notes: Representative slide scan images from both axial (A) and sagittal (B) slices. Animals were injected with 1 mg FITC labeled 500 kDa dextran 1 minute prior to sacrifice in order to mark blood vessels. Slides were scanned with 541 nm and 488 nm excitation to image polypeptide and dextran, respectively.

Abbreviations: ANOVA, analysis of variance; ELP, elastin-like polypeptide; FITC, fluorescein isothiocyanate; IN, intranasal; IV, intravenous.