. 2016 Sep 12;11(9):e0162630. doi: 10.1371/journal.pone.0162630

Table 3. Results of subgroup analysis according to treatment line, treatment regimens for Meta-Analysis.

Stratified analysis		No. of studies	Cases (AI /Control)	Heterogeneity		Pooled HR (95% CI)	Text for overall effect
Stratified analysis		No. of studies	Cases (AI /Control)	I² (%)	P value	Pooled HR (95% CI)	Z	P value
Treatment cycles	Less than 10 cycles	3	184/187	0.0	0.98	0.70 (0.50–0.98)	2.07	0.04
Treatment cycles	More than 10 cycles	1	50/51	-	-	0.23 (0.09–0.57)	3.20	0.001
Treatment regiment	Combining with chemotherapy	3	178/181	59	0.08	0.57 (0.39–0.58)	2.73	0.006
Treatment regiment	Comparing with or without chemotherapy	1	56/57	-	-	0.68 (0.41–1.14)	1.46	0.14