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Pretreatment of ARPE19 cells with 1 μM TubA (an HDAC6 specific inhibitor) for 1 h prevented the reduction in TEER seen with Glyc-Alb measured at 6 h post treatment. Values represent means ± SE of individual measurements normalized to average TEER at 0 h, analyzed by ANOVA. Column numbers represent n for each condition. *p<0.05. Legend: Alb, albumin; Glyc-alb, glycated-albumin; TEER, transepithelial electrical resistance; TubA, tubastatin-A.
