Skip to main content
. 2016 Sep 12;11(9):e0162632. doi: 10.1371/journal.pone.0162632

Fig 4. Effect of L2 on myocardial contractility in regional ischemia-reperfusion.

Fig 4

(A) Effect of L2 on left ventricular developed pressure (LVDP, mmHg). (B) Effect of L2 on LVDP after natriuretic peptide receptor antagonist isatin pretreatment. (C) Effect of L2 on LVDP after mitoKATP channel blocker 5-hydroxydecanote (5-HD) treatment. (D) Area under curve (AUC, absolute variation of LVDP x time). Myocardial infarction was induced by 30 min regional ischemia followed by 90 min reperfusion. Data are mean ± SEM. For number of animals see Table 2. ***, p<0.001 versus vehicle, †, p<0.05 versus corresponding group not treated with antagonist, $, p<0.05, $ $ $, p<0.001 versus stabilisation values.