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. 2016 Sep 6;5:81–89. doi: 10.2147/OV.S96915

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© 2016 Burke. This work is published and licensed by Dove Medical Press Limited

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SVV-001 in vivo response.

Notes: The heat map represents tumor response in PPTP xenograft models after a single injection of SVV-001 (3´10¹² vp/kg). A high level of antitumor activity is shown in red (MCR) and orange (CR) with no activity in green (PD). Adapted with permission from John Wiley and Sons. Morton CL, Houghton PJ, Kolb EA, et al. Initial testing of the replication competent Seneca Valley virus (NTX-010) by the pediatric preclinical testing program. Pediatr Blood Cancer. 2010;55(2):295–303.¹⁰ © 2010 John Wiley and Sons.

Abbreviations: SVV-001, Seneca Valley Virus isolate 001; PPTP, Pediatric Preclinical Testing Program; MCR, maintained complete response; CR, complete response; PD, progressive disease.