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. 2016 Sep 6;5:81–89. doi: 10.2147/OV.S96915

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© 2016 Burke. This work is published and licensed by Dove Medical Press Limited

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Viral clearance of SVV-001.

Notes: Viral clearance in the blood and stool over time after a single dose (A) and after two doses (B) of SVV-001 in the COG ADVL0911 pediatric trial. The arrow denotes timing of SVV-001 administration. Reproduced with permission from John Wiley and Sons. Burke MJ, Ahern C, Weigel BJ, et al. Phase I trial of Seneca Valley virus (NTX-010) in children with relapsed/refractory solid tumors: a report of the Children’s Oncology Group. Pediatr Blood Cancer. 2015;62(5):743–750.¹⁶ © 2015 John Wiley and Sons.

Abbreviations: SVV-001, Seneca Valley Virus isolate 001; COG, Children’s Oncology Group.