Table 2.

Selected randomized clinical trials of intravitreal corticosteroids: adverse events

Trial	Therapies studied	Summary of results
DRCR.net Protocol B, 3-year results33	Triamcinolone vs photocoagulation	Cataract surgery: 83% with triamcinolone 4 mg, 46% with triamcinolone 1 mg, 31% with photocoagulation; IOP increase ≥10 mmHg: 33% triamcinolone 4 mg, 18% triamcinolone 1 mg, 4% with photocoagulation
Maturi et al50	Dexamethasone insert vs sham injection	With 0.7 mg insert: 41.5% topical IOP lowering medications, 0.3% incisional glaucoma surgery
Pearson et al58	Fluocinolone surgical implant vs standard therapy	Cataract surgery: 91% with implant, 20% with standard therapy; IOP ≥30 mmHg: 61.4% with implant, 5.8% with standard therapy
Campochiaro et al62	Fluocinolone insert vs sham injection	IOP-lowering medication: 38.4% with 0.2 µg/day insert, 14.1% with sham; Incisional glaucoma surgery: 4.8% with 0.2 µg/day insert, 0.5% with sham
Parrish et al63	Fluocinolone insert vs sham injection	Incisional glaucoma surgery with 0.2 µg/day insert: 6.1% not previously treated with triamcinolone, 0% previously treated with triamcinolone

Abbreviations: DRCR.net, Diabetic Retinopathy Clinical Research Network; IOP, intraocular pressure.