Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 7;9:5553–5560. doi: 10.2147/OTT.S105787

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Xian et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Kaplan–Meier survival curves for gastric cancer, with comparisons evaluated using the log-rank test.

Notes: (A) PHGDH mRNA levels in GC specimens determined by real-time PCR. PHGDH mRNA was significantly higher in GC tissues than in their paired peritumoral counterparts (P=0.007). (B) Overall survival was significantly shorter in patients with PHGDH-high expression (green line: 1) vs PHGDH-low expression (blue line: 0). (C) Overall survival was significantly shorter in patients with preoperative CEA-high levels (green line: 1) vs CEA-low levels (blue line: 0). (D) Advanced TNM stage significantly worsened overall survival compared with early TNM stage: TNM IIIc and IV (light blue line: 7), TNM IIIb (red line: 6), TNM IIIa (yellow line: 5), TNM IIb (purple line: 4), TNM IIa (light yellow line: 3), TNM Ib (green line: 2), and TNM Ia +0 (blue line: 1).

Abbreviations: CEA, carcinoembryonic antigen; GC, gastric cancer; PCR, polymerase chain reaction; PHGDH, phosphoglycerate dehydrogenase; mRNA, messenger RNA; TNM, tumor node metastasis.