Table II. Data on Silver-Stained Nucleolar Organizer Regions (AgNORs) of Individuals at Various Ages With or Without Multiple Endocrine Neoplasia Type-II.
| Age group | No.of subjects | No. of cells | AgNOR average ± S.D. per cell | Range | AgNOR Data per chromosome group | ||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
|
|
D group | G group | |||||||
| (M) | (F) |
|
|
||||||
| Mean ± S.D. | Range | Mean ± S.D. | Range | ||||||
| Control subjects | |||||||||
| Fetal (19—30 weeks gestation) | 1 | 7 | 149 | 8.18 ± 0.69 | 7.2—9.3 | 5.1 ± 0.5 | 4.4—5.8 | 3.0 ± 0.9 | 2.0—4.0 |
| 0—6 year olds | 3 | 5 | 160 | 8.31 ± 0.74 | 7.1—9.5 | 4.9 ± 0.5 | 4.0—5.8 | 3.4 ± 0.7 | 2.0—4.0 |
| 7—13 year olds | 3 | 5 | 165 | 8.42 ± 0.86 | 7.2—9.6 | 4.9 ± 0.7 | 3.5—5.7 | 3.5 ± 0.5 | 2.6—4.0 |
| 14—23 year olds | 4 | 4 | 165 | 8.82 ± 0.86 | 7.3—9.8 | 5.3 ± 0.6 | 4.2—5.9 | 3.6 ± 0.4 | 3.1—4.0 |
| 24—44 year olds | 3 | 5 | 155 | 8.11 ± 0.70 | 7.1—9.1 | 5.1 ± 0.4 | 4.3—5.7 | 3.0 ± 0.6 | 2.1—3.8 |
| 45—65 year olds | 3 | 4 | 128 | 7.85 ± 0.85 | 6.5—8.6 | 4.6 ± 0.8 | 3.8—5.2 | 3.2 ± 0.3 | 2.8—3.6 |
| > 65 year olds | 4 | 4 | 148 | 7.99 ± 0.76 | 6.8—9.1 | 4.9 ± 0.7 | 3.7—5.8 | 3.1 ± 0.4 | 2.6—3.9 |
| Multiple endocrine neoplasia-type II | |||||||||
| 25—58 year olds | 6 | 7 | 262 | 8.52 ± 0.73 | 6.9—9.4 | 5.1 ± 0.8 | 3.0—5.9 | 3.4 ± 0.4 | 2.8—4.0 |