Table 2.
IVF/ICSI outcomes of half-dose depot GnRH-agonist and GnRH-antagonist protocols in which corifollitropin alfa was used
Depot GnRH agonist+ corifollitropin alfa group (n=45) | GnRH antagonist+ corifollitropin alfa group (n=49) | ||
---|---|---|---|
Positive β-hCG | 18 (40%) | 18 (36.7%) | 0.93 |
CPR | 16 (35.6%) | 16 (32.7) | 0.95 |
BPR | 2 (4.44%) | 2 (4.08%) | NS |
Implantation rate (%) | 32.5±6.82 | 36.25±8.58 | 0.73 |
Singleton pregnancy rate | 13/16 (81.25) | 12/16 (75%) | NS |
Twin pregnancy rate | 3/16 (18.75%) | 4/16 (25%) | NS |
OHSS rate | 0 | 0 | NS |
Cancel rate | 5 (11.1%) | 9 (18.4%) | 0.46 |
CPR: clinical pregnancy rate; BPR: biochemical pregnancy rate; GnRH: gonadotropin hormone-releasing hormone; IVF/ICSI: in vitro fertilization/intracytoplasmic sperm injection; hCG: human chorionic gonadotropin; OHSS: ovarian hyperstimulation syndrome