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. 2016 Aug 1;44(4):201–205. doi: 10.5152/TJAR.2016.53138

Table 2.

Questions and answers about the pharmacological properties of local anaesthetics (%)

Correct Incorrect
Presence of many protective layers around many myelinated and unmyelinated nerve fibres creates a major obstacle for the introduction of clinically used local anaesthetics 66.2 33.8
Local anaesthetics are divided into two groups as amide- and ester-structured 97.8 2.2
Sodium channels are the main target for the activity of local anaesthetics 88.4 11.6
Bupivacaine is ester-structured 55.3 44.7
Prilocaine is ester-structured 48.7 51.3
The addition of epinephrine enhances the effectiveness of the local anaesthetic 83.5 16.5
Maximum single dose for bupivacaine is 600 mg 70.8 29.2
Bupivacaine has the shortest half-life 84.5 15.5