Table 3.
Meta-analysis of TLR4 polymorphism with the risk of SLE.
| Polymorphism | Genetic model | Test of association | Test of heterogeneity | ||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P | Model | I 2 | P | ||
| D299G | Dominant | 1.31 | 0.96, 1.80 | 0.09 | Fixed | 0.0% | 0.432 |
| Recessive | 2.18 | 0.65, 7.24 | 0.21 | Fixed | 53.3% | 0.143 | |
| Allele | 1.30 | 0.98, 1.73 | 0.07 | Fixed | 16.6% | 0.301 | |
|
| |||||||
| T399I | Dominant | 1.18 | 0.85, 1.64 | 0.33 | Fixed | 0.0% | 0.710 |
| Recessive | 2.52 | 0.66, 9.63 | 0.18 | Fixed | 62.7% | 0.102 | |
| Allele | 1.20 | 0.89, 1.62 | 0.24 | Fixed | 0.0% | 0.538 | |