Table 1.

Relationship between the investigated parameters and the plasma D-dimer and serum CEA levels.

	n = 134	D-dimer		CEA
		Median (ng/mL)	p D-dimer	Median (ng/mg)	p CEA
Tumor localization
Colon	94	1.10	0.472∗	26.1	0.621∗
Rectum	40	0.96		26.9
Differentiation
Well	18	1.10	0.04α	26.8	0.207α
Middle	94	1.15		27.3
Poor/mucinous	22	1.80		33.1
Tumor diameter (mm)
<20 mm	6	1.31	0.276α	2.8	0.615α
20–50 mm	86	1.25		23.5
>50 mm	42	1.28		36.6
Wall invasion (N0, M0)
T1	5	0.14	0.0001+	2.9	0.0001+
T2	16	0.39		3.7
T3	70	0.80		15.6
T4	18	1.30		50.5
Lymph node (any T, M0)
Negative	52	0.55	0.0004∗	4.8	0.02∗
Positive	54	0.96		40.8
Metastasis (any T and N)
No	106	0.78	>0.001∗	3.20	>0.001∗
Yes	28	2.53		4.80
Stage
1	14	0.30	0.001+	3.20	0.001+
2	34	0.66		4.80
3	58	0.98		12.5
4	28	2.53		102.7

^∗Mann–Whitney U test; ^αKruskal-Wallis test; ⁺Spearman's rank correlation test.