Table 2.

Evaluation of the prognostic significance of the parameters using the univariate analysis of variance.

	HR	95% CI	p
Age	0.4629	0.2219–0.9657	0.168
Sex (female/male)	1.0748	0.5016–2.3032	0.852
Tumor size	1.6839	0.8512–3.3310	0.134
Tumor localization (colon/rectum)	0.4190	0.1707–1.0285	0.057
Differentiation (well/other)	0.0413	0.4811–2.2542	0.918
Wall invasion (T)	2.3222	1.1121–4.8501	0.02
Lymph node invasion (yes/no)	0.1312	0.0304–0.5661	0.006
Metastasis (yes/no)	6.4082	2.5226–16.2787	0.0001
Stage	3.6337	1.9390–6.8095	0.0001
D-dimer	2.1274	1.6926–2.6730	<0.0001
CEA	1.0008	1.0014–1.0109	0.01

HR: hazard ratio; CI: confidence interval.