Table 1.
Patient clinical history.
| Patient | Age1 | Major comorbidities2 | KS location | Time since KS diagnosis (months) | Length of HIV infection (years) | Anatomical location of biopsy | Concentration (ng/μL) | Number of env sequences | Number of nef sequences | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RNA | DNA | RNA | DNA | RNA | DNA | |||||||
| KS1 | 34 | Lymphoma, MAC, PCP, cytomegalovirus | Skin, pleura, lungs, trachea, lymph node, liver, adrenal glands | Unknown | 7 | KS skin | 144 | 154 | 22 | 8 | 24 | 9 |
| KS lymph node | 168 | 276 | 13 | 21 | 14 | 21 | ||||||
| Lymph node | 120 | 12.1 | 37 | 22 | 35 | 26 | ||||||
| Kidney | >200 | 8.18 | 5 | 0 | 9 | 0 | ||||||
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| KS2 | 31 | BCBL | Skin, pleura, lungs, esophagus, small bowel | ~5 | Unknown | KS skin | 165 | 44 | 14 | 10 | 18 | 12 |
| KS small bowel | 192 | 9.84 | 4 | 0 | 5 | 0 | ||||||
| Liver | 191 | 8.42 | 0 | 0 | 0 | 0 | ||||||
| Spleen | 190 | 13.9 | 23 | 1 | 31 | 2 | ||||||
|
| ||||||||||||
| KS3 | 28 | Aggressive KS | Skin, pleura, lungs, trachea, esophagus, small bowel, colon, rectum, iliac lymph nodes, mesenteric lymph nodes, para-aortic lymph nodes, paratracheal lymph nodes | ~1 | 9 | KS skin | 49 | 51 | 6 | 2 | 2 | 6 |
| KS small bowel | 164 | 39.4 | 16 | 25 | 14 | 24 | ||||||
| Liver | 161 | 33.4 | 14 | 5 | 15 | 5 | ||||||
| Stomach | 78.2 | 40.2 | 24 | 8 | 20 | 8 | ||||||
1Age in years; 2MAC: Mycobacterium avium complex; PCP: Pneumocystis pneumonia; BCBL: body cavity based lymphoma.