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Scheme of the Na+-NQR complex showing the subunit composition and redox cofactors. NADH is oxidized by FAD in NqrF. Electrons move trough the enzyme to the final electron ubiquinone in the following order: FAD → 2Fe-2S center → FMNC → FMNB → riboflavin. The 2Fe-2S center → FMNC step controls Na+ uptake, and the FMNB → riboflavin step controls Na+ release. The arrows indicate the translocation of Na+ through NqrB, -D, and -E.
