Table 1.
Patients’ characteristics
| Characteristics | All patients (n = 40) | Survivors day 90 (n = 23) | Non-survivors day 90 (n = 17) | p |
|---|---|---|---|---|
| Age (years) | 48 (34–58) | 45 (30–60) | 53 (37–69) | 0.004 |
| Male, n (%) | 26 (65 %) | 15 (68 %) | 11 (61 %) | 0.64 |
| BMI (kg/m2) | 28 (25–32) | 28 (25–31) | 30 (24–36) | 0.51 |
| Comorbidities, n (%) | ||||
| Hypertension | 8 (20 %) | 2 (9 %) | 6 (33 %) | 0.07 |
| Heart failure | 1 (2.5 %) | 0 (0 %) | 1 (6 %) | 0.26 |
| Diabetes mellitus | 2 (5 %) | 0 (0 %) | 2 (12 %) | 0.11 |
| COPD | 2 (5 %) | 1 (4.5 %) | 1 (6 %) | 0.88 |
| CKD | 2 (5 %) | 1 (4.5 %) | 1 (6 %) | 0.26 |
| Stroke | 3 (7.5 %) | 1 (4.5 %) | 2 (12 %) | 0.43 |
| TBSA (%) | 41 (29–56) | 36 (30–42) | 59 (42–76) | 0.013 |
| Full-thickness BSA burned (%) | 21 (10–14) | 20 (10–30) | 49 (33–65) | 0.016 |
| Inhalation injury, n (%) | 16 (40 %) | 6 (27 %) | 10 (55 %) | 0.07 |
| Delay from trauma (h) | 3 (2–5) | 3 (1–5) | 2 (1–3) | 0.45 |
| SAPS II | 31 (23–50) | 26 (10–42) | 50 (31–69) | 0.004 |
| ABSI | 9 (7–11) | 8 (7–9) | 12 (10–14) | 0.008 |
| SOFA score on day 1 | 3 (1–4) | 1 (0–2) | 4 (2–6) | 0.01 |
| ICU length of stay (days) | 34 (18–53) | 42 (20–64) | 22 (8–36) | 0.01 |
| Mechanical ventilation, n (%) | 34 (90 %) | 18 (78 %) | 16 (94 %) | 0.4 |
| Use of norepinephrine in the first 24 h, n (%) | 11 (29 %) | 5 (22 %) | 6 (35 %) | 0.44 |
| Sepsis in the first 7 days, n (%) | 22 (55 %) | 11 (47 %) | 11 (64 %) | 0.56 |
| Surgery in the first 24 h, n (%)a | 17 (42.5 %) | 7 (30 %) | 10 (59 %) | 0.13 |
| Pre-hospital administered fluid volume (mL/kg/h/%TBSA) | 0.15 (0.10–0.23) | 0.16 (0.13–0.23) | 0.14 (0.06–0.30) | 0.48 |
| Administered fluid volume in the first 24 h (mL/kg/%TBSA) | 3.7 (2.2–4.8) | 3.5 (1.8–4.7) | 3.8 (2.6–6.0) | 0.57 |
Data are median (interquartile range 25th–75th percentile), or n (%)
BMI body mass index, COPD chronic obstructive pulmonary disease, CKD chronic kidney disease, TBSA total body surface area burn, BSA body surface area, SAPS II Simplified Acute Physiology Score II, ABSI Abbreviated Burn Severity Index, SOFA Sequential Organ Failure Assessment, ICU intensive care unit
aEscharotomy and/or fasciotomy